By Ricardo Azziz (auth.), Ricardo Azziz MD, MPH, MBA, John E. Nestler MD, Didier Dewailly MD (eds.)
The box of androgen extra issues has complex considerably because the unique e-book of this publication. The Androgen extra Society (AES) was once based to assemble investigators within the box. a greater knowing of the screening, development, and molecular genetics of nonclassic adrenal hyperplasia (NCAH) has more desirable the medical care and diagnostic accuracy of those sufferers. New standards for the analysis of the polycystic ovary syndrome (PCOS) have been proposed in Rotterdam, standards that experience led to controversy and, confidently, initiation of recent stories. The organization of insulin resistance with PCOS has been bolstered, and the function of metformin in tre- ing the infertility of the PCOS has been demonstrated. hazards for diabetes and, extra cont- versially, heart problems in girls with PCOS have got big research. Our knowing of the epidemiology and monetary impression of those issues has increased, emphasizing their serious significance. those are yet a couple of highlights of the way the terrain has replaced in a comparatively short time period. according to those advances, the name of this e-book has been revised to mirror the becoming significance of PCOS because the so much usual androgen extra sickness in girls, and arguably, because the one who may need the main severe antagonistic effects for common health and wellbeing. There are fewer chapters to supply a extra targeted elucidation of the world. numerous chapters have been penned via new (and younger) authors who're carrying out state of the art learn within the field.
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Additional resources for Androgen Excess Disorders in Women: Polycystic Ovary Syndrome and Other Disorders
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Geller DH, Auchus RJ, Miller WL. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5. Mol Endocrinol 1999;13:167–175. 34. Pandey AV, Mellon SH, Miller WL. Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. J Biol Chem 2003;278:2837–2844. 35. Miller WL. The molecular basis of adrenarche: A hypothesis. Acta Pediatr 1999;88 (Suppl 433):60–66. 36. Flück CE, Tajima T, Pandey AV, et al.
Androgen Excess Disorders in Women: Polycystic Ovary Syndrome and Other Disorders by Ricardo Azziz (auth.), Ricardo Azziz MD, MPH, MBA, John E. Nestler MD, Didier Dewailly MD (eds.)